Now showing items 1-2 of 2

    • Community carriage of ESBL-producing Escherichia coli and Klebsiella pneumoniae: a cross-sectional study of risk factors and comparative genomics of carriage and clinical isolates 

      Raffelsberger, Niclas Peter; Buczek, Dorota Julia; Svendsen, Kristian; Småbrekke, Lars; Pöntinen, Anna Kaarina; Löhr, Iren Høyland; Andreassen, Lotte Leonore Eivindsdatter; Simonsen, Gunnar Skov; Sundsfjord, Arnfinn Ståle; Gravningen, Kirsten; Samuelsen, Ørjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-12)
      The global prevalence of infections caused by extended-spectrum βlactamase-producing Enterobacterales (ESBL-E) is increasing, and for Escherichia coli, observations indicate that this is partly driven by community-onset cases. The ESBL-E population structure in the community is scarcely described, and data on risk factors for carriage are conflicting. Here, we report the prevalence and population ...
    • Detection of Klebsiella pneumoniae human gut carriage: a comparison of culture, qPCR, and whole metagenomic sequencing methods 

      Lindstedt, Kenneth; Buczek, Dorota Julia; Pedersen, Torunn Annie; Hjerde, Erik; Raffelsberger, Niclas Peter; Suzuki, Yutaka; Brisse, Sylvain; Holt, Kathryn E.; Samuelsen, Ørjan; Sundsfjord, Arnfinn (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-31)
      Klebsiella pneumoniae is an important opportunistic healthcare-associated pathogen and major contributor to the global spread of antimicrobial resistance. Gastrointestinal colonization with K. pneumoniae is a major predisposing risk factor for infection and forms an important hub for the dispersal of resistance. Current culture-based detection methods are time consuming, give limited intra-sample ...